An interesting question. This [1] suggests that the contact lens market is ~$10B, which is in the realm of YC aspirations. That market is likely to grow as the purchasing-power of people globally continues to grow. Sounds like YC to me.
except how is this market captured? Seems to be more supply-chain and scale, or R&D in the actual product. These guys appear to hope for the former, but not sure how they can beat the bigger players other than some vague comments akin to leveraging supplier and customer data. The smaller startups that have built online presence have already focused really well on streamlining the experience, order fulfillment and customer service at low prices; how much margin is left to be the new player and compete on price?