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A few personal anecdotes:

Sativa has a stronger anxiety producing effect for me than Indica if I remember correctly. I really only smoke sativa. That said, some sativa strains produce more anxiety than others. But when I do experience marijuana-induced anxiety, it tends to be very near the beginning of the high and subsides pretty quickly.



Just the opposite for me. I find Sativa to generally lift my mood. I'm more likely to be social, carry on conversations and have interesting thoughts. Compared to Indica, which for me has more of a lazy effect. That may be great for serious pain management, but if I'm laid up my mind is more likely to go in different directions.


The mood lifting effects happen with sativa for me too. But if I happen to feel anxiety from it, it will be a short lived bit at the beginning.




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